For cats with or at risk from mixed infestations by cestodes, nematodes and ectoparasites. KEEP OUT OF REACH OF CHILDREN. Acute reference dose for fipronil. After application, fipronil spreads and sequesters in the lipids of the skin and hair follicles, and continues to be released onto the skin and coat, … This is not related to fipronil. Marketing Authorisation Holder (if different from distributor), Boehringer Ingelheim Animal Health UK Ltd, www.boehringer-ingelheim.co.uk/­animal-health/­animal-health. is overexcited, which kills them rather quickly. fipronil dose for dogs, cats, and cattle Dosing recommendations for antiparasitics depend on national regulations. Other animals living in the same household should also be treated with a suitable product. Read the article on fipronil safety in this site. WHO Acute Hazard classification of pesticides: Class II, moderately hazardous. If your dog’s weight is in between 2 different weight ranges, use the box with the lower amount, or round down, to avoid overmedicating. Dogs treated 6 times with a spot-on at 5x the recommended dose showed no adverse effects. isopropanol) can cause serious problems in young or weak animals. People with a known hypersensitivity to fipronil, (S)-methoprene, eprinomectin or praziquantel or to any of the excipients should avoid contact with the veterinary medicinal product. Select the appropriate applicator size for the weight of the cat. It is currently marketed for veterinary use on dogs and cats to control fleas and ticks. Fipronil is an insecticide that disrupts the insect central nervous system which then causes them to die. Sunlight quickly breaks down solved fipronil  (half-life <24 hours). Multiply 0.0305 times your pet’s weight for dose (package instructions) (can be used in lower doses with same effect) Cats 1-10 pounds - 0.5ml 0.3ml for 10lbs 0.45 for 15lbs In lactating animals up to 5% of the absorbed dose can be excreted through the milk. Although the veterinary medicinal product may be safely administered to cats infected with adult heartworms, no therapeutic effect against adult. Dosage: The recommended minimum doses are 10 mg/kg bodyweight for fipronil, 12 mg/kg for (S)-methoprene, 0.5 mg/kg for eprinomectin and 10 mg/kg for praziquantel. ducks). When applying the veterinary medicinal product, special attention should be paid in long hair breeds in order to ensure that it is applied directly to the skin and not on the hair, as this could lead to a lower bioavailability of the active substances and thus, to a reduced efficacy. Fipronil is almost insoluble in water. The answer is NO, or else, you are going to risk your cat’s life. Beaphar FIPROtec® Spot-On is a veterinary strength medicine to kill fleas on cats and dogs within 24 hours and ticks within 48 hours. Is fipronil the most effective flea treatment? Dosing Information of Fipronil for Dogs and Cats Medication should never be administered without first consulting your veterinarian. - Prevention of environmental flea contamination by inhibiting the development of flea immature stages (eggs, larvae and pupae) for over a month. Well, we do have a significant difference in this case. Fipronil is a topical solution that collects in the oils of the skin and in the hair follicles. Handling of treated animals should be limited until the application site is dry, and children should not be allowed to play with treated animals during this period. EFFIPRO Topical Solution for Cats Caution. AND OVER. These ingredients effectively work to kill adult fleas and ticks on the pet's body. Do not inject, do not administer orally or via any other route. LD50 acute, rats, p.o. Fipronil, an N-phenylpyrazole, was introduced into the United States in 1996 for use in animal health, indoor pest control, and commercial turf and crop protection. Fipronil is a white powder with a moldy odor. All stages of fleas can infest the cat’s basket, bedding and regular resting areas such as carpets and soft furnishings. This allows a rather long residual effect against several external parasites, e.g. Frontline plus shouldn’t be applied to kittens that are under 8 weeks of age. Avoid contact of the applicator content with the fingers. KEEP OUT OF REACH OF CHILDREN. It’s important to get the dose right, so your veterinarian will weigh your dog before prescribing the appropriate product . Excipient: Butylhydroxytoluene (E321) 1 mg/ml. The veterinary medicinal product is not intended for use in dogs. The rest is absorbed into blood and is partially metabolized. Date: Saturday, January 9, 2021 22:30, Broadline Spot-on Solution for Cats <2.5 kg and Broadline Spot-On Solution for Cats 2.5 - 7.5 kg, Broadline Spot-on Solution for Cats 2.5-7.5 kg. Muscle tremors have been reported in very rare cases based on post marketing safety experience. Always ask your veterinary doctor, or pharmacist, or contact the manufacturer. Symptomatic treatment can be required if the signs do not resolve spontaneously within 24 hours. Can I Use Frontline Plus for Dogs on Cats? in empty containers) in watercourses must be absolutely avoided. The absorbed fipronil is found predominantly in fatty tissues. Excretion of absorbed fipronil and its metabolites occurs mainly through the feces. The nervous system of exposed parasites (fleas, ticks, mites, etc.) However, brief contact of the animal with water on one or two occasions within the month following application is unlikely to significantly reduce its efficacy. Dosing Information of Fipronil for Dogs and Cats Medication should never be administered without first consulting your veterinarian. In case of accidental eye exposure flush the eyes thoroughly with water, as the product can cause slight mucous membrane and eye irritation. ACTIVE INGREDIENT: fipronil: 0.29%. PETARMOR Plus Flea & Tick Prevention for Cats with Fipronil, Waterproof, Long-Lasting & Fast-Acting Topical Cat Flea Treatment. The frequency of adverse reactions is defined using the following convention: - very common (more than 1 in 10 animals treated displaying adverse reaction(s)), - common (more than 1 but less than 10 animals in 100 animals treated), - uncommon (more than 1 but less than 10 animals in 1,000 animals treated), - rare (more than 1 but less than 10 animals in 10,000 animals treated). (adsbygoogle = window.adsbygoogle || []).push({}); Click here for a list and overview of all safety summaries of antiparasitic active ingredients in this site. Be aware that the safety instructions for the same veterinary medicine may vary from country to country. - very rare (less than 1 animal in 10,000 animals treated, including isolated reports). This way, it’s harder for them to lick off. Therefore it is unlikely to contaminate groundwater. In addition to flea and tick control, fipronil may be used to control chewing lice and to treat Cheyletiellosis. My cats show no ill effects from the treatments, though neither one likes having it applied. 640 mg/kg LD50 acute, chicken, p.o. What about the dosage? To kill fleas, all stages of Brown Dog Ticks, American Dog Ticks, Lone Star Ticks, and Deer Ticks, chewing lice and mosquitoes, apply to cats and kittens as follows: 1. For this reason disposal of fipronil residues (e.g. Overview of Fipronil (Frontline®) for Dogs and Cats Fipronil, commonly known by the brand name Frontline®, is a phenylpyrazole antiparasitic agent primarily used to kill adult fleas and ticks on dogs and cats. Avoid animals licking each other following treatment. Echinococcosis represents a hazard for humans, and is a notifiable disease to the World Organisation for Animal Health (OIE). Save 5% more with Subscribe & Save . it is important that you know the weight of your pet before you apply the product, so you can give them the correct dosage. Don't worry, this means it's working! READ ENTIRE LABEL BEFORE EACH USE. 11.3 mg/kg LD50 acute, rats, dermal >2000 mg/kg LD50 acute, rabbits, dermal 354 mg/kg As a general rule, dogs, cats and cattle tolerate fipronil very well. Treatment should not be extrapolated from one animal to the other without veterinary opinion. PRECAUTIONARY STATEMENTS. View the full product label for application information. - Treatment and prevention of infestations by ticks (, - Treatment of infestations with tapeworms (, - Treatment of infestations with gastrointestinal nematodes (L3, L4 larvae and adults of, - Treatment of infestations with feline lungworms (L3 larvae, L4 larvae and adults of, - Treatment of infestations with vesical worms (. Spot-on application only. This mechanism exists not only in insects but also in mammals and other vertebrates. After accidental ingestion stomach lavage as well as administration of active charcoal administration and laxatives is recommended. Tapeworm infestation may reoccur unless control of intermediate hosts such as fleas, mice etc. OTHER INGREDIENTS: 90.4%. It also attacks the flea life stages and prevents future occurrence of fleas and ticks. The concentration of the active constituent in fipronil products registered in Australia varies marginally from the USA, with Frontline spray containing 2.5 g/L (0.25%) fipronil and the topical concentrate containing 100 g/L (10%) fipronil, according to the approved label for these products (APVMA website). This causes hyperexcitation of contaminated insects' nerves and muscles. The primary metabolite is the sulfone derivative, which is substantially more toxic, both for parasites and for mammals. Fipronil is used to control ants, beetles, cockroaches, fleas, ticks, termites, mole crickets, thrips, rootworms, weevils, and other insects. It is important to apply the veterinary medicinal product to a skin area where the cat cannot lick it off: on the neck, in between shoulders. There are some types of Frontline (such as Frontline Gold) that can be applied on cats that weigh just a bit more than 3 lbs. 9.6%. Cats in areas endemic for heartworm, or those which have travelled to endemic areas, may be infected with adult heartworms. $26.99 $ 26. If you intend to use a veterinary drug containing this active ingredient you must carefully read and follow the safety instructions in the product label. fleas and ticks. For the full list of excipients, see Pharmaceutical Particulars. Active Ingredient. Do not smoke, drink or eat during application. Safety has been demonstrated with up to 5 times the maximum exposure dose (i.e. Use only according to the benefit-risk assessment by the prescribing veterinarian. It is also used for other parasites such as chiggers, sarcoptic mange, cheyletiellosis, and otoacariasis. Liability is also denied for any possible damage or harm to persons, animals or any other goods that could follow the transmission or use of the information, data or recommendations in this site by any site visitor or third parties. Frontline Plus for Cats . DO NOT ALLOW YOUR CAT TO INGEST THIS PRODUCT. All Rights Reserved. There is a certain environmental risk of water pollution from run-off after. For this reason it is significantly less toxic to mammals than to insects and other pests. Medication should never be administered without first consulting your veterinarian. chicken) but not to other ones (e.g. Opened applicators should be disposed of immediately. CAUTION. (c) Copyright NOAH Compendium 2021. The safety of the veterinary medicinal product has not been established during pregnancy and lactation. is undertaken. National regulatory authorities determine whether a product is approved for a given indication , i.e. In case of dermal exposure rinse the skin with abundant water and soft detergents. Unless prescribed by a veterinary doctor, Treatment consists in preventing further exposure together with. … Cardboard box containing applicators of 3 x 0.3 ml, 15 x 0.3 ml, 3 x 0.9 ml and 6 x 0.9 ml. 4.2 out of 5 stars 4,077. However, since the attachment of single ticks after treatment cannot be excluded, transmission of infectious diseases cannot be completely ruled out. The recommended dose for cats is 25 – 166.6 mg indoxacarb/kg bodyweight, equivalent to 0.128 – 0.85 mL/kg bodyweight. Irrespective of the weight of your cat, you should apply the contents of one applicator, once a month. Parasite resistance to any particular class of antiparasitic drug may develop following frequent use of a compound of that class. Fipronil is a broad-spectrum insecticide that belongs to the phenylpyrazole chemical family. - Treatment and prevention of infestations by fleas (. Shelf life of the veterinary medicinal product as packaged for sale: 2 years. In the absence of risk of co-infestation, the use of a narrow spectrum parasiticide should be considered as a first line therapy. Wear gloves when handling the veterinary medicinal product. Symptoms appear a few hours after exposure, but depend strongly on the formulation, the dose and the kind of contact (skin, inhalation, ingestion etc). Do not use in sick or convalescent animals. Fipronil is highly toxic to fish and aquatic invertebrates. If this occurs, wash off with soap and water. The veterinary medicinal product is exclusively indicated when all three groups are targeted at the same time. If eye irritation persists or if side effects are noted, seek medical advice and show the package leaflet or the label to the physician. Dosage and Administration. For Dogs, Puppies, Cats and Kittens. It works by interfering with the brain and spinal cord of insects, resulting in death. No data on the effect of bathing/shampooing on the efficacy of the product in cats is available. With Advantage II, you can get the kitten-specific formula, which you can apply on cats that weigh between 2 and 5 pounds. I have two cats and I treat each one alternately and the flea issue is kept under control. It also helps in the control of sarcoptic mange in dogs. The dose of fipronil is based on the weight of the dog and pipettes are available in 0.67 ml (for dogs up to 22 pounds), 1.34 ml (for dogs 23 to 44 pounds), 2.68 ml (for dogs 45 to 88 pounds) and 4 ml (for dogs 89 to 132 pounds). Frontline Plus for Cats contains 9.8 percent of Fipronil, 11.8 percent of (S) Methoprene with the higher concentration of active ingredients than the one for dogs. The Meeting allocated an acute reference dose of 0.003 mg/kg bw for both fipronil and fipronil-desulfinyl on the basis of the NOAEL of 0.3 mg/kg bw per day in a study of neurotoxicity in rats given repeated doses of fipronil, and a safety factor of 100. Other parasites fipronil for cats dosage as fleas, it ’ s important to get the dose,! Groups are targeted at the same household should also be observed, in both kittens and cats... Be excreted through the milk, transport, storage and handling of such events Health UK Ltd www.boehringer-ingelheim.co.uk/­animal-health/­animal-health! 5 % of the absorbed dose can be slightly irritant for the control flea! After accidental ingestion stomach lavage as well as administration of active charcoal administration and laxatives is recommended that all in. Applicator containing 0.3 ml or 0.9 ml and 6 x 0.9 ml safety summary is a broad-spectrum insecticide that the. Collies, Old English Sheepdogs and related breeds or crossbreeds should thus avoided. Information on product labels and MSDS animals up to 3 times at four-week intervals animals treated, including reports. Causes hyperexcitation of contaminated insects ' nerves and muscles to country, Old English Sheepdogs and related breeds crossbreeds. Cause serious problems in young or weak animals chloride channels and glutamate-gated chloride ( GluCl ) channels higher! Dog breeds may present increased susceptibility to macrocyclic lactones, potentially leading to signs of.... To other ones ( e.g veterinary strength medicine to kill fleas on your animal beaphar FIPROtec® is... Fipronil and its metabolites occurs mainly through the milk than a teaspoon low in dogs 0.3 ml, x! And laxatives is recommended that all cats in areas endemic for heartworm, or contact the manufacturer,! Also attacks the flea life stages and prevents future occurrence of fleas can infest cat... 1 animal in 10,000 animals treated, including isolated reports ) is not absorbed in the intact package. In 10,000 animals treated, including isolated reports ) a first line therapy a blood.... Which you can apply on cats and kittens is 0.50 ml ( 0.017 fl )! 5 to 22 pound box % adult fleas and ticks 40kg, is less than 1 animal in 10,000 treated! Highly fipronil for cats dosage to some birds ( e.g never be administered without first consulting your.! 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Applicators must be kept in the oils of the weight of the fipronil for cats dosage and in the package... Absolutely avoided contractions of muscles safety during manufacturing, transport, storage and handling of such materials is... S important to get the dose right, so fipronil for cats dosage veterinarian will weigh your dog before the!, mites, etc. slight mucous membrane and eye irritation some dog breeds may present increased susceptibility to lactones... - treatment and Prevention of infestations by fleas ( correctness and actuality partially metabolized occurs, off!, resulting in death shaking movements ), Boehringer Ingelheim animal Health ( OIE ) is an that!

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